Microneedles
Microneedles are devices that are highly anticipated as a mechanism for applying pharmaceuticals broadly and minimally invasively into the shallow layers of the skin.
Our company is focused on the development of hollow microneedles utilizing our proprietary manufacturing technologies.
Our company is focused on the development of hollow microneedles utilizing our proprietary manufacturing technologies.
NEW
Microneedle Unit with Through-type Transverse Holes【3】
Our Strengths
1
The Transverse Holes Design of the Needles enables:
• Ensures the Strength of the Tip
• Shallow and Broad Injectable Delivery
2
Made of Biodegradable Resin:
• Biocompatibility
• Mass Production through Injection Molding
Our newly developed, integrated injection molding process (Patent Pending) provides higher reliability and significant cost savings compared to conventional bonding type.
The needle hub (Luer connector), which can be connected to a general-purpose syringe, is integrated injection molded with the microneedle.
*For reliable drug delivery, we recommend using the dedicated applicator.
*For reliable drug delivery, we recommend using the dedicated applicator.
In cooperation with Kinki Seiko Co., Ltd.
※We welcome inquiries regarding the integration of our technology and products into your company's diagnostic systems.
※We provide solutions that realize designs customized to meet a wide range of clinical applications and specific requirements.
※We provide solutions that realize designs customized to meet a wide range of clinical applications and specific requirements.
Bonding-type Hollow Microneedle 【1】【2】
Microneedles with transverse holes are made through the precise bonding of two micro molded components.
In vaccine experiments (in rats) showed that intradermal delivery using the microneedle produced higher immune activity compared to standard subcutaneous injection.
In vaccine experiments (in rats) showed that intradermal delivery using the microneedle produced higher immune activity compared to standard subcutaneous injection.
References
【1】“Fabrication of Bonding-Type Hollow Microneedle Array by Injection Molding and Evaluation of its Puncture Characteristics”
IEEJ Trans, SM, Vol.132, No.5, 133-138(2012).
Noriyuki Ogai, Ryo Sugimura(ASTI), Yoshihiro Takiguchi(GPI）
*IEEJ Distinguished Paper Award(2013)
【2】“Enhanced immunity in intradermal vaccination by novel hollow microneedles”
Skin Res. Technol. 1-6 (2018).
Noriyuki Ogai, et al.(ASTI), Hidekazu Fukamizu (Hamamatsu university School of Medicine)
【3】“Fabrication and Performance Evaluation of Microneedle Devices with Through-type Transverse Holes”
IEEJ Trans. SM, Vol.144, No.7, pp170-175(2024).
Noriyuki Ogai, Yasuhiro Toda(ASTI), Kosuke Hatazawa(Kinki Seiko）
*The 40th SENSOR SYMPOSIUM Poster Presentation Excellence Award Winner
Microneedle array for cosmetic
We are partnering with a leading cosmetics manufacturer on the collaborative development of next-generation microneedles, emphasizing both high efficacy and safety.
By utilizing our proprietary micro-mold and injection molding techniques, we have developed a unique microneedle array structure. We are proceeding commercialization supported by patent applications and joint presentations at academic conferences.
※Patent application 2024-512605
※IFSCC Conference 2024
By utilizing our proprietary micro-mold and injection molding techniques, we have developed a unique microneedle array structure. We are proceeding commercialization supported by patent applications and joint presentations at academic conferences.
※Patent application 2024-512605
※IFSCC Conference 2024
